![]() ![]() ![]() ![]() This can be expressed by the RAP index, which is based on the correlation between the amplitude of the ICP pulse wave and mean ICP. Intracranial compliance is the ability to compensate for increases in intracranial volume, i.e., cerebrospinal compensatory reserve. Children have several anatomical and physiological differences compared with adults, e.g., regarding optimal cerebral perfusion pressure (CPP) levels, cerebrovascular pressure reactivity, and intracranial compliance. It is important to gain more knowledge about the intracranial pressure dynamics in pediatric TBI when BCT is used. In a recent study we found that high-dose BCT in children with RICH was effective without causing unacceptable concomitant side effects and that the long-term clinical outcome was relatively favorable. ![]() In children BCT is not as well established as in adults. Barbiturate coma treatment (BCT) of refractory intracranial hypertension (RICH) is an established treatment option in adult TBI patients. TBI is also common in children who require particular concern in many respects. Despite modern neurointensive care (NIC), traumatic brain injury (TBI) remains a worldwide cause of mortality and morbidity, and treatment strategies remain challenging. ![]()
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